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What is Opana?
Opana, commonly known under the name of Oxymorphone is a potential analgesic that is used to treat moderate to severe pain that are induced in the body. It is produced in a semi synthetic state that was first developed by Endo Pharmaceuticals in 1955. The medical market of United States was introduced with this drug in 1959. Since then, it is the most used opioid medicine in the region for the purpose of treating severe pains in the patients undergoing surgeries and accidentals cases.
The most common brand name for Opana is Numorphan. It was derived for the analogies used for drugs that lied in the Roxicodone products lists. The most used and marketed salt for Roxicodone is the hydrochloride salt that can be used in several ways and combinations with other medicines. It is normally indicated for the use in patients who want relief from the moderate to severe pains. This medication is also commercially used in operation theatres as an anesthesia medicine. Several patients have been noticed to be cured from the acute ventricular failure and pulmonary diseases. The extended release tablets are used for management of chronic pains that are occurring in the bodies of patients who are already taking regular doses of strong opioids like this drug for a long period of time. In contrast to this, immediate release tablets are suggested to those patients who are suffering from pains even after use of extended release tablets.
How it works?
It is one of the most famous painkillers which are in the market. It is termed as an opioid drug which is used to treat pains in the body. It is also known as the relative of opium, looking on its specifications. Opium has been in use for thousands of years in the medicines as well as abuses. These drugs work by binding the neuro receptors that transfer pain signals from the source to brain. This makes the nerves sluggish and they don’t react actively to the signals. This brings relaxation to the body of the patient suffering from pain. It also works in the spinal nerves that bring pain by lowering their ability to sense the pain. This slow down process of the Opana also affects other parts of body as they slow down the performance of the nerves in the gut also. This induces constipation. So the resultant effects are the outcomes of these sluggish nerves.
It is generally a derivative of morphine which acts on the Central nervous system of the body and interferes with its normal processes. This abrupt interaction with the system changes the biochemical nature of the chemicals that are working in the brain and counter act with neuro transmitters. The more you use Opana, the more you are addicted to it. Its dependency and tolerance increases with its prolonged use. This is because our brain adjusts itself with a level where t works perfectly with the drug affecting other parts of body. It causes serious addiction in the person who abuses this drug.
Many people use this drug as recreational purpose. They don’t know the deadly effects of this drug and continue until they are addicted to it and no one can help them in this regard. Several companies have produced a version of this drug that makes the patients leave it after a certain period of time to avoid its use as a narcotic or abuse.
Dosage and administrations
- OPANA ER is administered at a frequency of twice daily (every 12 hours). Administer on an empty stomach, at least 1 hour prior to or 2 hours after eating.
- Use of OPANA ER as the First Opioid Analgesic
- Initiate treatment with OPANA ER with the 5 mg tablet orally every 12-hours.
- Use of OPANA ER in Patients who are not Opioid Tolerant
- The starting dose for patients who are not opioid tolerant is OPANA ER 5 mg orally every 12 hours. Patients who are opioid tolerant are those receiving, for one week or longer, at least 60 mg oral morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg oral Oxycodone per day, 8 mg oral hydromorphone per day, 25 mg oral Oxymorphone per day, or an equianalgesic dose of another opioid.
- Use of higher starting doses in patients who are not opioid tolerant may cause fatal respiratory depression.
Precautions and Warnings
Considering, Opana is the most potential drug used for the treatment in patients with pains; it comes with lot of precautions and warnings. Doctors suggest the patients to show their previous health record so that he can perfectly analyze and recommend you the perfect dose of medicines. If you have allergies that are related to opiate drugs, avoid taking this drug to make yourself light and healthy. Do not take this medicine even if you have
- Breathing problems that relate you to asthma
- Constipation or blockage in the intestines
- Any liver diseases
Serotonin syndrome is the condition which is caused, when the people get interacted with other medicines in combination with Opana. Make sure that you stop your intake of other opioids or opiates which you are using for any other purpose. Tell your doctor if you are suffering from mental illness or headaches, infections or symptoms of vomiting and nausea. Make sure that you can safely take Opana as a medicine by telling the doctor if you have any diseases like
- Problems in breathing or lung infections
- Head injuries, seizures or migraines
- Alcohol or narcotic addiction
- Problems in urinating
- Problems in liver of kidney
- Thyroid or glandular problems
Several side effects are noticed in the patients who consume Opana as a regular drug. These side effects prove to be fatal sometimes. For example, problems related with respiratory system can increase once you abuse Opana. Other side effects are
- Blurred vision
- decreased urination
- difficult or labored breathing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- dry mouth
- fast, pounding, racing, or irregular heartbeat or pulse
- pounding in the ears
- rapid breathing
- sunken eyes
- swelling of the hands, ankles, or feet
- tightness in the chest
- unusual tiredness or weakness
- wrinkled skin
Some rare and less common effects can be described as below. These side effects do not need regular medical attention. You body gets use to it after a certain period of time and you will feel normal after a while.
- Abdominal or stomach pain
- chest pain or discomfort
- cold sweats
- decrease in consciousness
- decrease in urine volume
- difficulty in passing urine (dribbling)
- difficulty with sleeping
- difficulty with swallowing
- drowsiness to profound coma
- hives, itching, or skin rash
- irregular, slow, or shallow breathing